How to Take RSO: Exploring the Different Modes of Administration

Rick Simpson Oil (RSO) has become a popular natural remedy for managing chronic conditions, especially among patients seeking relief from cancer, pain, inflammation, or sleep disorders. But one of the most important things to know when starting with RSO is this:

👉 How you take it matters.

RSO is extremely potent and versatile. Depending on your condition, goals, and tolerance, the method of administration can affect how quickly you feel it, how long it lasts, and whether you experience psychoactive effects.

In this post, we’ll break down the main ways to take RSO, from swallowing it to rubbing it on your skin.

Oral Ingestion (Swallowing)

This is the most common way people take RSO. It involves swallowing a small dose — typically about the size of a grain of rice — either directly or by mixing it into food or capsules.

✅ Pros:

• Long-lasting effects (6–8 hours or more).

• Excellent for full-body relief (e.g., pain, cancer, insomnia).

• Simple and discreet.

⚠️ Cons:

• Delayed onset (1–2 hours).

• Can be very potent due to liver processing (THC becomes 11-hydroxy-THC).

📝 Tip: Start low and go slow. A tiny dose can go a long way.

Sublingual (Under the Tongue)

By placing a small amount under your tongue, RSO is absorbed through the mucous membranes directly into your bloodstream. This allows for faster effects than swallowing.

✅ Pros:

• Faster onset (15–45 minutes).

• Bypasses the liver for a cleaner, lighter high.

• More control over effects.

⚠️ Cons:

• Bitter, sticky taste.

• May irritate the mouth.

📝 Tip: Hold it under your tongue for at least 60 seconds before swallowing.

Topical Application (On the Skin)

If you’re using RSO for localized issues like skin cancer, rashes, or joint pain, applying it directly to the skin can be very effective.

✅ Pros:

• No psychoactive effects.

• Directly targets the problem area.

• Great for skin conditions or joint inflammation.

⚠️ Cons:

• Won’t help with internal or systemic issues.

• Can be sticky and messy.

📝 Tip: Mix with coconut oil or shea butter for smoother application.

Rectal (Suppositories)

Though less commonly talked about, this method is extremely efficient — especially for patients who can’t tolerate THC’s psychoactive effects or who struggle with swallowing.

✅ Pros:

• Fast absorption.

• High bioavailability.

• Minimal to no high.

⚠️ Cons:

• May feel uncomfortable or unfamiliar.

• Requires preparation or purchase of suppositories.

📝 Tip: Use cocoa butter-based suppositories for easy use and storage.

Inhalation (Smoking or Vaping)

Though not traditional, some users vaporize RSO or dab it (once properly prepared). This offers instant relief, making it ideal for breakthrough symptoms.

✅ Pros:

• Effects kick in within minutes.

• Easy to control dose.

• Ideal for anxiety, pain, or nausea.

⚠️ Cons:

• Effects wear off quickly (2–3 hours).

• Not all vaporizers are compatible with raw RSO.

• Harsh on the lungs.

📝 Tip: Never vape raw RSO unless it’s formulated for vaporization — it must be properly diluted and purged of solvents.

Mixed Into Food or Edibles

RSO can also be cooked into meals or mixed into smoothies and baked goods — just like any cannabis concentrate.

✅ Pros:

• Long-lasting, full-body effects.

• Can mask the taste with creative recipes.

• Great for daily use.

⚠️ Cons:

• Easy to overdose without proper measuring.

• Takes a while to kick in (1–2 hours).

📝 Tip: Always mix thoroughly to ensure even distribution in your recipe.

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Final Thoughts

RSO isn’t a one-size-fits-all solution. Whether you’re managing a serious illness or just looking for natural symptom relief, choosing the right method of administration makes all the difference.

• Need long-lasting full-body relief? Go oral.

• Want faster effects without smoking? Try sublingual.

• Treating a skin issue or localized pain? Use it topically.

• Can’t tolerate THC? Rectal administration might be best.

No matter how you take it, remember: RSO is potent. Start with a rice-grain-sized dose and work your way up gradually.